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Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC-MS.
Mehl, John T; Sleczka, Bogdan G; Ciccimaro, Eugene F; Kozhich, Alexander T; Gilbertson, Deb G; Vuppugalla, Ragini; Huang, Christine S; Stevens, Brenda; Mo, Jingjie; Deyanova, Ekaterina G; Wang, Yun; Huang, Richard Yc; Chen, Guodong; Olah, Timothy V.
Afiliación
  • Mehl JT; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Sleczka BG; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Ciccimaro EF; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Kozhich AT; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Gilbertson DG; Bristol Myers Squibb Co, Seattle, WA, USA.
  • Vuppugalla R; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Huang CS; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Stevens B; Bristol Myers Squibb Co, Seattle, WA, USA.
  • Mo J; Johnson & Johnson, Malvern, PA, USA.
  • Deyanova EG; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Wang Y; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Huang RY; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Chen G; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
  • Olah TV; Bristol Myers Squibb Co, Princeton, NJ 08543, USA.
Bioanalysis ; 8(15): 1611-1622, 2016 Aug.
Article en En | MEDLINE | ID: mdl-27397670
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Base de datos: MEDLINE Asunto principal: Asparagina / Ácido Aspártico / Anticuerpos Monoclonales Idioma: En Revista: Bioanalysis Año: 2016 Tipo del documento: Article
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PubMed Links

Base de datos: MEDLINE Asunto principal: Asparagina / Ácido Aspártico / Anticuerpos Monoclonales Idioma: En Revista: Bioanalysis Año: 2016 Tipo del documento: Article