Statin-centric versus low-density lipoprotein-centric approach for atherosclerotic cardiovascular disease prevention: a Singapore perspective.
Singapore Med J
; 57(7): 360-7, 2016 Jul.
Article
en En
| MEDLINE
| ID: mdl-27439304
ABSTRACT
The link between cholesterol levels and atherosclerotic cardiovascular disease (ASCVD) is well-established. In Singapore, there is an increasing prevalence of risk factors for ASCVD. Like many Asian countries, Singapore's population is rapidly ageing and increasingly sedentary, which predisposes individuals to chronic health problems. Current international and local guidelines recommend statin therapy for the primary and secondary prevention of ASCVD. However, despite the effectiveness of statin therapy, some studies have highlighted that Asian patients with cardiovascular disease are not achieving target lipid goals. Furthermore, it is widely believed that the responses of Asians (both patients and physicians) to statin therapy are different from those of their Western counterparts. Experts convened in 2014 to determine the impact of current guidelines on clinical practice in Singapore. This review summarises the key findings and recommendations of these guidelines, and presents key principles to aid clinicians to manage the cardiovascular risk of their patients more effectively.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
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Inhibidores de Hidroximetilglutaril-CoA Reductasas
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Aterosclerosis
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Lipoproteínas LDL
Tipo de estudio:
Etiology_studies
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Guideline
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Risk_factors_studies
País/Región como asunto:
Asia
Idioma:
En
Revista:
Singapore Med J
Año:
2016
Tipo del documento:
Article