Pharmacokinetics and comparative metabolic profiling of iridoid enriched fraction of Picrorhiza kurroa - An Ayurvedic Herb.

Zahiruddin, Sultan; Khan, Washim; Nehra, Rinki; Alam, Md Javed; Mallick, Md Nasar; Parveen, Rabea; Ahmad, Sayeed

Zahiruddin, Sultan; Khan, Washim; Nehra, Rinki; Alam, Md Javed; Mallick, Md Nasar; Parveen, Rabea; Ahmad, Sayeed.

Afiliación

Zahiruddin S; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India.
Khan W; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India.
Nehra R; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India.
Alam MJ; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India.
Mallick MN; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India.
Parveen R; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India.
Ahmad S; Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110062, India. Electronic address: sahmad_jh@yahoo.co.in.

J Ethnopharmacol ; 197: 157-164, 2017 Feb 02.

Article en En | MEDLINE | ID: mdl-27469200

Asunto(s)

Iridoides/metabolismo; Iridoides/farmacocinética; Picrorhiza/química; Extractos Vegetales/metabolismo; Extractos Vegetales/farmacocinética; Plantas Medicinales/química; Plantas Medicinales/metabolismo; Acetofenonas/sangre; Administración Oral; Animales; Cinamatos/sangre; Semivida; Glucósidos Iridoides/sangre; Iridoides/química; Masculino; Medicina Ayurvédica; Extractos Vegetales/química; Raíces de Plantas/química; Raíces de Plantas/metabolismo; Ratas; Ratas Wistar; Rizoma/química; Rizoma/metabolismo

Palabras clave

Apocynin (PubChem CID: 2214); Iridoids; Metabolomics; Pharmacokinetics; Picrorhiza kurroa; Picroside I (PubChem CID: 6440892); Picroside II (PubChem CID: 9849283); UPLC-MS

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Plantas Medicinales / Extractos Vegetales / Picrorhiza / Iridoides Idioma: En Revista: J Ethnopharmacol Año: 2017 Tipo del documento: Article

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