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Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1.
Bakr, Ali; Köcher, Sabrina; Volquardsen, Jennifer; Petersen, Cordula; Borgmann, Kerstin; Dikomey, Ekkehard; Rothkamm, Kai; Mansour, Wael Y.
Afiliación
  • Bakr A; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Köcher S; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Volquardsen J; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Petersen C; Department of Radiotherapy and Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Borgmann K; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Dikomey E; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Rothkamm K; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Mansour WY; Laboratory of Radiobiology & Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Oncotarget ; 7(36): 57679-57693, 2016 Sep 06.
Article en En | MEDLINE | ID: mdl-27494840

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteínas Portadoras / Proteínas de Unión a Telómeros / Reparación del ADN / Roturas del ADN de Doble Cadena / Poli(ADP-Ribosa) Polimerasa-1 / Proteína 1 de Unión al Supresor Tumoral P53 Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteínas Portadoras / Proteínas de Unión a Telómeros / Reparación del ADN / Roturas del ADN de Doble Cadena / Poli(ADP-Ribosa) Polimerasa-1 / Proteína 1 de Unión al Supresor Tumoral P53 Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article