Silencing Prion Protein in HT29 Human Colorectal Cancer Cells Enhances Anticancer Response to Fucoidan.

Yun, Chul Won; Yun, Seungpil; Lee, Jun Hee; Han, Yong-Seok; Yoon, Yeo Min; An, Daniel; Lee, Sang Hun

Yun, Chul Won; Yun, Seungpil; Lee, Jun Hee; Han, Yong-Seok; Yoon, Yeo Min; An, Daniel; Lee, Sang Hun.

Afiliación

Yun CW; Medical Science Research Institute, Soonchunhyang University, Seoul Hospital, Seoul, Republic of Korea Department of Medical Bioscience, Soonchunhyang University, Asan, Republic of Korea.
Yun S; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A.
Lee JH; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A. jhlee0407@sch.ac.kr.
Han YS; Medical Science Research Institute, Soonchunhyang University, Seoul Hospital, Seoul, Republic of Korea Department of Medical Bioscience, Soonchunhyang University, Asan, Republic of Korea.
Yoon YM; Medical Science Research Institute, Soonchunhyang University, Seoul Hospital, Seoul, Republic of Korea Department of Medical Bioscience, Soonchunhyang University, Asan, Republic of Korea.
An D; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A.
Lee SH; Medical Science Research Institute, Soonchunhyang University, Seoul Hospital, Seoul, Republic of Korea Department of Medical Bioscience, Soonchunhyang University, Asan, Republic of Korea jhlee0407@sch.ac.kr.

Anticancer Res ; 36(9): 4449-58, 2016 09.

Article en En | MEDLINE | ID: mdl-27630281

Asunto(s)

Antineoplásicos/química; Silenciador del Gen; Polisacáridos/química; Proteínas Priónicas/genética; Animales; Apoptosis; Caspasa 3/metabolismo; Ciclo Celular; Línea Celular Tumoral; Movimiento Celular; Proliferación Celular; Neoplasias del Colon/tratamiento farmacológico; Células HT29; Humanos; Inmunohistoquímica; Masculino; Ratones; Ratones Endogámicos BALB C; Molécula-1 de Adhesión Celular Endotelial de Plaqueta/química; Proteínas Priónicas/metabolismo; Antígeno Nuclear de Célula en Proliferación/metabolismo; Interferencia de ARN; ARN Interferente Pequeño/metabolismo; Factor A de Crecimiento Endotelial Vascular/metabolismo

Palabras clave

Fucoidan; cellular prion protein; migration; proliferation

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Base de datos: MEDLINE Asunto principal: Polisacáridos / Silenciador del Gen / Proteínas Priónicas / Antineoplásicos Idioma: En Revista: Anticancer Res Año: 2016 Tipo del documento: Article

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