Oxytocin provides protection against diabetic polyneuropathy in rats.

Erbas, Oytun; Taskiran, Dilek; Oltulu, Fatih; Yavasoglu, Altug; Bora, Saylav; Bilge, Okan; Çinar, Bilge Piri; Peker, Gönül

Erbas, Oytun; Taskiran, Dilek; Oltulu, Fatih; Yavasoglu, Altug; Bora, Saylav; Bilge, Okan; Çinar, Bilge Piri; Peker, Gönül.

Afiliación

Erbas O; a Department of Physiology , Istanbul Bilim University School of Medicine , Istanbul , Turkey.
Taskiran D; b Department of Physiology , Ege University School of Medicine , Izmir , Turkey.
Oltulu F; c Department of Histology and Embryology , Ege University School of Medicine , Izmir , Turkey.
Yavasoglu A; c Department of Histology and Embryology , Ege University School of Medicine , Izmir , Turkey.
Bora S; b Department of Physiology , Ege University School of Medicine , Izmir , Turkey.
Bilge O; d Department of Anatomy , Ege University School of Medicine , Izmir , Turkey.
Çinar BP; e Department of Neurology , Giresun State Hospital , Giresun , Turkey.
Peker G; b Department of Physiology , Ege University School of Medicine , Izmir , Turkey.

Neurol Res ; 39(1): 45-53, 2017 Jan.

Article en En | MEDLINE | ID: mdl-27881053

Asunto(s)

Neuropatías Diabéticas/prevención & control; Oxitócicos/uso terapéutico; Oxitocina/uso terapéutico; Análisis de Varianza; Animales; Glucemia/efectos de los fármacos; Peso Corporal/efectos de los fármacos; Caspasa 3/metabolismo; Caspasa 8/metabolismo; Neuropatías Diabéticas/inducido químicamente; Neuropatías Diabéticas/fisiopatología; Modelos Animales de Enfermedad; Electromiografía; Potenciales Evocados Motores/efectos de los fármacos; Potenciales Evocados Motores/fisiología; Glutatión/sangre; Peróxidos Lipídicos/sangre; Masculino; Actividad Motora/efectos de los fármacos; Músculo Esquelético/efectos de los fármacos; Músculo Esquelético/patología; Factor de Crecimiento Nervioso/metabolismo; Ratas; Ratas Sprague-Dawley; Células de Schwann/efectos de los fármacos; Células de Schwann/patología; Nervio Ciático/patología; Estreptozocina/toxicidad; Proteína X Asociada a bcl-2/metabolismo

Palabras clave

CMAPs: Compound muscle action potentials; DNP: Diabetic polyneuropathy; DRG: Dorsal root ganglion; Diabetes mellitus; Diabetic polyneuropathy; EMG; EMG: Electromyography; GSH: Glutathione; MDA: Malondialdehyde; NCV: Neuron conduction velocity; OT: Oxytocin; Oxidative stress; Oxytocin; PKC: Protein kinase C; ROS: Reactive oxygen species; STZ: Streptozotocin; TBARS: Thiobarbituric acid reactive substance; TNF-α: Tumor necrosis factor- alpha

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Base de datos: MEDLINE Asunto principal: Oxitócicos / Oxitocina / Neuropatías Diabéticas Tipo de estudio: Prognostic_studies Idioma: En Revista: Neurol Res Año: 2017 Tipo del documento: Article

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