Genetically edited pigs lacking CD163 show no resistance following infection with the African swine fever virus isolate, Georgia 2007/1.

Popescu, Luca; Gaudreault, Natasha N; Whitworth, Kristen M; Murgia, Maria V; Nietfeld, Jerome C; Mileham, Alan; Samuel, Melissa; Wells, Kevin D; Prather, Randall S; Rowland, Raymond R R

Popescu, Luca; Gaudreault, Natasha N; Whitworth, Kristen M; Murgia, Maria V; Nietfeld, Jerome C; Mileham, Alan; Samuel, Melissa; Wells, Kevin D; Prather, Randall S; Rowland, Raymond R R.

Afiliación

Popescu L; Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Gaudreault NN; Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA. Electronic address: nng5757@vet.k-state.edu.
Whitworth KM; Division of Animal Science, College of Food Agriculture and Natural Resources, University of Missouri, Columbia, MO, USA.
Murgia MV; Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Nietfeld JC; Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Mileham A; Genus, plc, DeForest, Wisconsin, USA.
Samuel M; Division of Animal Science, College of Food Agriculture and Natural Resources, University of Missouri, Columbia, MO, USA.
Wells KD; Division of Animal Science, College of Food Agriculture and Natural Resources, University of Missouri, Columbia, MO, USA.
Prather RS; Division of Animal Science, College of Food Agriculture and Natural Resources, University of Missouri, Columbia, MO, USA.
Rowland RRR; Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.

Virology ; 501: 102-106, 2017 01 15.

Article en En | MEDLINE | ID: mdl-27898335

Asunto(s)

Virus de la Fiebre Porcina Africana/fisiología; Fiebre Porcina Africana/genética; Animales Modificados Genéticamente/metabolismo; Receptores de Superficie Celular/deficiencia; Porcinos/genética; Fiebre Porcina Africana/metabolismo; Fiebre Porcina Africana/virología; Virus de la Fiebre Porcina Africana/genética; Animales; Animales Modificados Genéticamente/genética; Animales Modificados Genéticamente/virología; Antígenos CD/genética; Antígenos de Diferenciación Mielomonocítica/genética; Técnicas de Inactivación de Genes; Georgia; Macrófagos/metabolismo; Macrófagos/virología; Receptores de Superficie Celular/genética; Receptores Virales/genética; Receptores Virales/metabolismo; Porcinos/metabolismo; Porcinos/virología

Palabras clave

African swine fever; CD163; Receptor; Virus

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Porcinos / Animales Modificados Genéticamente / Receptores de Superficie Celular / Fiebre Porcina Africana / Virus de la Fiebre Porcina Africana País/Región como asunto: America do norte Idioma: En Revista: Virology Año: 2017 Tipo del documento: Article

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