Role of genomic factors beyond thymidylate synthase in the prediction of response to 5-fluorouracil.

Peters, Godefridus J; Smid, K; Meijer, E; van Groeningen, C J; Leon, L G

Peters, Godefridus J; Smid, K; Meijer, E; van Groeningen, C J; Leon, L G.

Afiliación

Peters GJ; a Department of Medical Oncology , VU University Medical Center , Amsterdam , The Netherlands.
Smid K; a Department of Medical Oncology , VU University Medical Center , Amsterdam , The Netherlands.
Meijer E; a Department of Medical Oncology , VU University Medical Center , Amsterdam , The Netherlands.
van Groeningen CJ; a Department of Medical Oncology , VU University Medical Center , Amsterdam , The Netherlands.
Leon LG; b Amstelland Hospital , Amstelveen , The Netherlands.

Nucleosides Nucleotides Nucleic Acids ; 35(10-12): 595-603, 2016 Dec.

Article en En | MEDLINE | ID: mdl-27906628

Asunto(s)

Antimetabolitos Antineoplásicos/farmacología; Neoplasias Colorrectales/tratamiento farmacológico; Fluorouracilo/farmacología; Timidilato Sintasa/genética; Adulto; Anciano; Antimetabolitos Antineoplásicos/uso terapéutico; Cromosomas Humanos Par 12/genética; Neoplasias Colorrectales/genética; Neoplasias Colorrectales/mortalidad; Hibridación Genómica Comparativa; Femenino; Fluorouracilo/uso terapéutico; Humanos; Estimación de Kaplan-Meier; Masculino; Persona de Mediana Edad; Resultado del Tratamiento

Palabras clave

5-fluorouracil; DNA copy number profile; colorectal cancer; thymidylate synthase

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Base de datos: MEDLINE Asunto principal: Timidilato Sintasa / Neoplasias Colorrectales / Fluorouracilo / Antimetabolitos Antineoplásicos Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Nucleosides Nucleotides Nucleic Acids Asunto de la revista: BIOQUIMICA Año: 2016 Tipo del documento: Article

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