Your browser doesn't support javascript.
loading
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen.
Cheeseman, Matthew D; Chessum, Nicola E A; Rye, Carl S; Pasqua, A Elisa; Tucker, Michael J; Wilding, Birgit; Evans, Lindsay E; Lepri, Susan; Richards, Meirion; Sharp, Swee Y; Ali, Salyha; Rowlands, Martin; O'Fee, Lisa; Miah, Asadh; Hayes, Angela; Henley, Alan T; Powers, Marissa; Te Poele, Robert; De Billy, Emmanuel; Pellegrino, Loredana; Raynaud, Florence; Burke, Rosemary; van Montfort, Rob L M; Eccles, Suzanne A; Workman, Paul; Jones, Keith.
Afiliación
  • Cheeseman MD; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Chessum NE; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Rye CS; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Pasqua AE; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Tucker MJ; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Wilding B; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Evans LE; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Lepri S; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Richards M; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Sharp SY; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Ali S; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Rowlands M; Division of Structural Biology at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • O'Fee L; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Miah A; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Hayes A; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Henley AT; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Powers M; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Te Poele R; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • De Billy E; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Pellegrino L; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Raynaud F; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Burke R; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • van Montfort RL; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Eccles SA; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Workman P; Division of Structural Biology at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
  • Jones K; Cancer Research UK Cancer Therapeutics Unit at The Institute of Cancer Research , London SW7 3RP, United Kingdom.
J Med Chem ; 60(1): 180-201, 2017 01 12.
Article en En | MEDLINE | ID: mdl-28004573
Asunto(s)
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Quinolinas / Factores de Transcripción / Proteínas Nucleares / Proteínas Portadoras / Proteínas de Unión al ADN / Amidas Tipo de estudio: Prognostic_studies Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Quinolinas / Factores de Transcripción / Proteínas Nucleares / Proteínas Portadoras / Proteínas de Unión al ADN / Amidas Tipo de estudio: Prognostic_studies Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article