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Inhibition of RORγT Skews TCRα Gene Rearrangement and Limits T Cell Repertoire Diversity.
Guo, Yanxia; MacIsaac, Kenzie D; Chen, Yi; Miller, Richard J; Jain, Renu; Joyce-Shaikh, Barbara; Ferguson, Heidi; Wang, I-Ming; Cristescu, Razvan; Mudgett, John; Engstrom, Laura; Piers, Kyle J; Baltus, Gretchen A; Barr, Kenneth; Zhang, Hongjun; Mehmet, Huseyin; Hegde, Laxminarayan G; Hu, Xiao; Carter, Laura L; Aicher, Thomas D; Glick, Gary; Zaller, Dennis; Hawwari, Abbas; Correll, Craig C; Jones, Dallas C; Cua, Daniel J.
Afiliación
  • Guo Y; Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA.
  • MacIsaac KD; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Chen Y; Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA.
  • Miller RJ; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Jain R; Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA.
  • Joyce-Shaikh B; Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA.
  • Ferguson H; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Wang IM; Merck Research Laboratories, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Cristescu R; Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA.
  • Mudgett J; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.
  • Engstrom L; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Piers KJ; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Baltus GA; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Barr K; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Zhang H; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Mehmet H; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Hegde LG; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Hu X; Lycera Corp, 2600 Plymouth Road, Ann Arbor, MI 48109, USA.
  • Carter LL; Lycera Corp, 2600 Plymouth Road, Ann Arbor, MI 48109, USA.
  • Aicher TD; Lycera Corp, 2600 Plymouth Road, Ann Arbor, MI 48109, USA.
  • Glick G; Lycera Corp, 2600 Plymouth Road, Ann Arbor, MI 48109, USA.
  • Zaller D; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Hawwari A; King Abdullah International Medical Research Center (KAIMRC), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City Hospital, Ministry of National Guard Health Affairs, Mail Code 520, P.O. Box 6664, Al Hasa 31982, Kingdom of Saudi Arabia.
  • Correll CC; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Jones DC; Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA.
  • Cua DJ; Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA. Electronic address: daniel.cua@merck.com.
Cell Rep ; 17(12): 3206-3218, 2016 12 20.
Article en En | MEDLINE | ID: mdl-28009290
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T alfa-beta / Encefalomielitis Autoinmune Experimental / Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares / Timocitos Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Rep Año: 2016 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T alfa-beta / Encefalomielitis Autoinmune Experimental / Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares / Timocitos Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Rep Año: 2016 Tipo del documento: Article