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Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.
Profilo, Emanuela; Peña-Altamira, Luis Emiliano; Corricelli, Mariangela; Castegna, Alessandra; Danese, Alberto; Agrimi, Gennaro; Petralla, Sabrina; Giannuzzi, Giulia; Porcelli, Vito; Sbano, Luigi; Viscomi, Carlo; Massenzio, Francesca; Palmieri, Erika Mariana; Giorgi, Carlotta; Fiermonte, Giuseppe; Virgili, Marco; Palmieri, Luigi; Zeviani, Massimo; Pinton, Paolo; Monti, Barbara; Palmieri, Ferdinando; Lasorsa, Francesco Massimo.
Afiliación
  • Profilo E; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Peña-Altamira LE; Department of Pharmacy and BioTechnology, University of Bologna, Bologna 40126, Italy.
  • Corricelli M; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara 44121, Italy.
  • Castegna A; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Danese A; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara 44121, Italy.
  • Agrimi G; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Petralla S; Department of Pharmacy and BioTechnology, University of Bologna, Bologna 40126, Italy.
  • Giannuzzi G; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Porcelli V; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Sbano L; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara 44121, Italy.
  • Viscomi C; MRC-Mitochondrial Biology Unit, Cambridge, UK; Fondazione IRCCS Istituto Neurologico "C. Besta", Milan, Italy.
  • Massenzio F; Department of Pharmacy and BioTechnology, University of Bologna, Bologna 40126, Italy.
  • Palmieri EM; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Giorgi C; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara 44121, Italy.
  • Fiermonte G; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy.
  • Virgili M; Department of Pharmacy and BioTechnology, University of Bologna, Bologna 40126, Italy.
  • Palmieri L; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy; Institute of Biomembranes and Bioenergetics, Consiglio Nazionale delle Ricerche, Bari 70126, Italy.
  • Zeviani M; MRC-Mitochondrial Biology Unit, Cambridge, UK; Fondazione IRCCS Istituto Neurologico "C. Besta", Milan, Italy.
  • Pinton P; Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara 44121, Italy.
  • Monti B; Department of Pharmacy and BioTechnology, University of Bologna, Bologna 40126, Italy.
  • Palmieri F; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', Bari 70125, Italy; Institute of Biomembranes and Bioenergetics, Consiglio Nazionale delle Ricerche, Bari 70126, Italy. Electronic address: ferdinando.palmieri@uniba.it.
  • Lasorsa FM; Institute of Biomembranes and Bioenergetics, Consiglio Nazionale delle Ricerche, Bari 70126, Italy. Electronic address: fm.lasorsa@ibbe.cnr.it.
Biochim Biophys Acta Mol Basis Dis ; 1863(6): 1422-1435, 2017 06.
Article en En | MEDLINE | ID: mdl-28235644
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Regulación hacia Abajo / Ácido Aspártico / Sistemas de Transporte de Aminoácidos / Proteínas Mitocondriales / Proliferación Celular / Neuronas Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Regulación hacia Abajo / Ácido Aspártico / Sistemas de Transporte de Aminoácidos / Proteínas Mitocondriales / Proliferación Celular / Neuronas Idioma: En Revista: Biochim Biophys Acta Mol Basis Dis Año: 2017 Tipo del documento: Article