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Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Bataille, Carole J R; Brennan, Méabh B; Byrne, Simon; Davies, Stephen G; Durbin, Matthew; Fedorov, Oleg; Huber, Kilian V M; Jones, Alan M; Knapp, Stefan; Liu, Gu; Nadali, Anna; Quevedo, Camilo E; Russell, Angela J; Walker, Roderick G; Westwood, Robert; Wynne, Graham M.
Afiliación
  • Bataille CJ; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Brennan MB; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Byrne S; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Davies SG; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK. Electronic address: steve.davies@chem.ox.ac.uk.
  • Durbin M; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Fedorov O; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, UK.
  • Huber KV; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Jones AM; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Knapp S; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford, UK.
  • Liu G; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Nadali A; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
  • Quevedo CE; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Russell AJ; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK. Electronic address: angela.russell@chem.ox.ac.uk.
  • Walker RG; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
  • Westwood R; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
  • Wynne GM; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK.
Bioorg Med Chem ; 25(9): 2657-2665, 2017 05 01.
Article en En | MEDLINE | ID: mdl-28341403
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rodanina / Sulfonamidas / Proteínas Proto-Oncogénicas / Proteínas Serina-Treonina Quinasas / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-pim-1 / Tiazolidinas Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rodanina / Sulfonamidas / Proteínas Proto-Oncogénicas / Proteínas Serina-Treonina Quinasas / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-pim-1 / Tiazolidinas Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article