Sensitive luminescent reporter viruses reveal appreciable release of hepatitis C virus NS5A protein into the extracellular environment.

Eyre, Nicholas S; Aloia, Amanda L; Joyce, Michael A; Chulanetra, Monrat; Tyrrell, D Lorne; Beard, Michael R

Eyre, Nicholas S; Aloia, Amanda L; Joyce, Michael A; Chulanetra, Monrat; Tyrrell, D Lorne; Beard, Michael R.

Afiliación

Eyre NS; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia; Centre for Cancer Biology, SA Pathology, Adelaide, Australia. Electronic address: nicholas.eyre@adelaide.edu.au.
Aloia AL; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Joyce MA; Department of Medical Microbiology and Immunology and the La Ka Shing Institute of Virology, Katz Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Canada.
Chulanetra M; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
Tyrrell DL; Department of Medical Microbiology and Immunology and the La Ka Shing Institute of Virology, Katz Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Canada.
Beard MR; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia; Centre for Cancer Biology, SA Pathology, Adelaide, Australia.

Virology ; 507: 20-31, 2017 07.

Article en En | MEDLINE | ID: mdl-28395182

Asunto(s)

Líquido Extracelular/virología; Hepacivirus/metabolismo; Hepatitis C/virología; Luciferasas/metabolismo; Proteínas no Estructurales Virales/metabolismo; Animales; Genes Reporteros; Hepacivirus/genética; Humanos; Luciferasas/genética; Ratones; Proteínas Recombinantes de Fusión/genética; Proteínas Recombinantes de Fusión/metabolismo; Proteínas no Estructurales Virales/genética

Palabras clave

Exosome; Hepatitis C virus; Luciferase; NS5A; Virus assembly; Virus replication

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Hepatitis C / Proteínas no Estructurales Virales / Hepacivirus / Líquido Extracelular / Luciferasas Tipo de estudio: Diagnostic_studies Idioma: En Revista: Virology Año: 2017 Tipo del documento: Article

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