Effect of Y6, an epigallocatechin gallate derivative, on reversing doxorubicin drug resistance in human hepatocellular carcinoma cells.

Wen, Yan; Zhao, Rui-Qiang; Zhang, Yun-Kai; Gupta, Pranav; Fu, Li-Xiang; Tang, An-Zhou; Liu, Bu-Ming; Chen, Zhe-Sheng; Yang, Dong-Hua; Liang, Gang

Wen, Yan; Zhao, Rui-Qiang; Zhang, Yun-Kai; Gupta, Pranav; Fu, Li-Xiang; Tang, An-Zhou; Liu, Bu-Ming; Chen, Zhe-Sheng; Yang, Dong-Hua; Liang, Gang.

Afiliación

Wen Y; Department of Pharmacy, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, P.R. China.
Zhao RQ; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.
Zhang YK; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.
Gupta P; Department of Biochemistry and Molecular Biology, School of Preclinical Medicine, Guangxi Medical University, Nanning 530021, P.R. China.
Fu LX; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.
Tang AZ; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.
Liu BM; College of Pharmacy, Guangxi Medical University, Nanning 530021, P.R. China.
Chen ZS; Department of Otolaryngology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, P.R. China.
Yang DH; Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards, Guangxi Institute of Chinese Medicine and Pharmaceutical Sciences, Nanning 530022, P.R. China.
Liang G; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, USA.

Oncotarget ; 8(18): 29760-29770, 2017 May 02.

Article en En | MEDLINE | ID: mdl-28423656

Asunto(s)

Antineoplásicos/farmacología; Catequina/análogos & derivados; Doxorrubicina/farmacología; Resistencia a Antineoplásicos/efectos de los fármacos; Miembro 1 de la Subfamilia B de Casetes de Unión a ATP/genética; Miembro 1 de la Subfamilia B de Casetes de Unión a ATP/metabolismo; Antineoplásicos/química; Apoptosis/efectos de los fármacos; Apoptosis/genética; Carcinoma Hepatocelular/tratamiento farmacológico; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Catequina/química; Catequina/farmacología; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Supervivencia Celular/genética; Células Cultivadas; Relación Dosis-Respuesta a Droga; Resistencia a Antineoplásicos/genética; Expresión Génica; Humanos; Subunidad alfa del Factor 1 Inducible por Hipoxia/genética; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo; Neoplasias Hepáticas/tratamiento farmacológico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo

Palabras clave

Y6; doxorubicin; epigallocatechin-3-gallate (EGCG); multidrug resistance; resistance reversal agent

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Doxorrubicina / Catequina / Resistencia a Antineoplásicos / Antineoplásicos Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article

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