Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors.

Pinto, Navin; Park, Julie R; Murphy, Erin; Yearley, Jennifer; McClanahan, Terri; Annamalai, Lakshmanan; Hawkins, Douglas S; Rudzinski, Erin R

Pinto, Navin; Park, Julie R; Murphy, Erin; Yearley, Jennifer; McClanahan, Terri; Annamalai, Lakshmanan; Hawkins, Douglas S; Rudzinski, Erin R.

Afiliación

Pinto N; Division of Hematology/Oncology, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, Washington.
Park JR; Division of Hematology/Oncology, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, Washington.
Murphy E; Merck Research Laboratories, Palo Alto, California.
Yearley J; Merck Research Laboratories, Palo Alto, California.
McClanahan T; Merck Research Laboratories, Palo Alto, California.
Annamalai L; Merck Research Laboratories, Palo Alto, California.
Hawkins DS; Division of Hematology/Oncology, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, Washington.
Rudzinski ER; Department of Laboratories, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.

Pediatr Blood Cancer ; 64(11)2017 Nov.

Article en En | MEDLINE | ID: mdl-28488345

Asunto(s)

Antígeno B7-H1/metabolismo; Biomarcadores de Tumor/metabolismo; Neoplasias/metabolismo; Proteína 2 Ligando de Muerte Celular Programada 1/metabolismo; Receptor de Muerte Celular Programada 1/metabolismo; Antígeno B7-H1/genética; Biomarcadores de Tumor/genética; Niño; Humanos; Técnicas para Inmunoenzimas; Estadificación de Neoplasias; Neoplasias/patología; Pronóstico; Proteína 2 Ligando de Muerte Celular Programada 1/genética; Receptor de Muerte Celular Programada 1/genética; ARN Mensajero/análisis; ARN Mensajero/genética

Palabras clave

PD-1; PD-L1; PD-L2; cancer immunotherapy; immune checkpoint inhibition

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Antígeno B7-H1 / Proteína 2 Ligando de Muerte Celular Programada 1 / Receptor de Muerte Celular Programada 1 / Neoplasias Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Pediatr Blood Cancer Asunto de la revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Año: 2017 Tipo del documento: Article

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