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Prediction of sustained fetal toxicity induced by ketoprofen based on PK/PD analysis using human placental perfusion and rat toxicity data.
Tanaka, Shingo; Kanagawa, Takeshi; Momma, Kazuo; Hori, Satoko; Satoh, Hiroki; Nagamatsu, Takeshi; Fujii, Tomoyuki; Kimura, Tadashi; Sawada, Yasufumi.
Afiliación
  • Tanaka S; Graduate School of Pharmaceutical Science, University of Tokyo, Tokyo, Japan.
  • Kanagawa T; Department of Maternal-Fetal Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
  • Momma K; Department of Pediatric Cardiology, Tokyo Women's Medical University Hospital, Tokyo, Japan.
  • Hori S; Graduate School of Pharmaceutical Science, University of Tokyo, Tokyo, Japan.
  • Satoh H; Graduate School of Pharmaceutical Science, University of Tokyo, Tokyo, Japan.
  • Nagamatsu T; Department of Obstetrics and Gynecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Fujii T; Department of Obstetrics and Gynecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
  • Kimura T; Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Sawada Y; Graduate School of Pharmaceutical Science, University of Tokyo, Tokyo, Japan.
Br J Clin Pharmacol ; 83(11): 2503-2516, 2017 Nov.
Article en En | MEDLINE | ID: mdl-28635050
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Antiinflamatorios no Esteroideos / Cetoprofeno / Dolor de la Región Lumbar / Conducto Arterial / Modelos Biológicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Br J Clin Pharmacol Año: 2017 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Antiinflamatorios no Esteroideos / Cetoprofeno / Dolor de la Región Lumbar / Conducto Arterial / Modelos Biológicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Br J Clin Pharmacol Año: 2017 Tipo del documento: Article