The Drosophila simulans Y chromosome interacts with the autosomes to influence male fitness.
J Evol Biol
; 30(10): 1821-1825, 2017 Oct.
Article
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| MEDLINE
| ID: mdl-28703322
ABSTRACT
The Y chromosome should degenerate because it cannot recombine. However, male-limited transmission increases selection efficiency for male-benefit alleles on the Y, and therefore, Y chromosomes should contribute significantly to variation in male fitness. This means that although the Drosophila Y chromosome is small and gene-poor, Y-linked genes are vital for male fertility in Drosophila melanogaster and the Y chromosome has large male fitness effects. It is unclear whether the same pattern is seen in the closely related Drosophila simulans. We backcrossed Y chromosomes from three geographic locations into five genetic backgrounds and found strong Y and genetic background effects on male fertility. There was a significant Y-background interaction, indicating substantial epistasis between the Y and autosomal genes affecting male fertility. This supports accumulating evidence that interactions between the Y chromosome and the autosomes are key determinants of male fitness.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Cromosoma Y
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Cromosomas
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Aptitud Genética
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Drosophila simulans
Idioma:
En
Revista:
J Evol Biol
Asunto de la revista:
BIOLOGIA
Año:
2017
Tipo del documento:
Article