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HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model.
Melo, Esther; Oertle, Philipp; Trepp, Carolyn; Meistermann, Hélène; Burgoyne, Thomas; Sborgi, Lorenzo; Cabrera, Alvaro Cortes; Chen, Chia-Yi; Hoflack, Jean-Christophe; Kam-Thong, Tony; Schmucki, Roland; Badi, Laura; Flint, Nicholas; Ghiani, Zeynep Eren; Delobel, Fréderic; Stucki, Corinne; Gromo, Giulia; Einhaus, Alfred; Hornsperger, Benoit; Golling, Sabrina; Siebourg-Polster, Juliane; Gerber, Francoise; Bohrmann, Bernd; Futter, Clare; Dunkley, Tom; Hiller, Sebastian; Schilling, Oliver; Enzmann, Volker; Fauser, Sascha; Plodinec, Marija; Iacone, Roberto.
Afiliación
  • Melo E; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland. Electronic address: esther.melo@roche.com.
  • Oertle P; Biozentrum and the Swiss Nanoscience Institute, University of Basel, Basel 4056, Switzerland.
  • Trepp C; Department of Ophthalmology, Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Bern 3010, Switzerland.
  • Meistermann H; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Burgoyne T; Institute of Ophthalmology, University College London, London EC1V9EL, United Kingdom.
  • Sborgi L; Biozentrum and the Swiss Nanoscience Institute, University of Basel, Basel 4056, Switzerland.
  • Cabrera AC; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Chen CY; Institute of Molecular Medicine and Cell Research, University of Freiburg, Freiburg D-79104, Germany.
  • Hoflack JC; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Kam-Thong T; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Schmucki R; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Badi L; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Flint N; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Ghiani ZE; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Delobel F; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Stucki C; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Gromo G; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Einhaus A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Hornsperger B; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Golling S; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Siebourg-Polster J; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Gerber F; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Bohrmann B; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Futter C; Institute of Ophthalmology, University College London, London EC1V9EL, United Kingdom.
  • Dunkley T; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Hiller S; Biozentrum and the Swiss Nanoscience Institute, University of Basel, Basel 4056, Switzerland.
  • Schilling O; Institute of Molecular Medicine and Cell Research, University of Freiburg, Freiburg D-79104, Germany; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg D-79104, Germany.
  • Enzmann V; Department of Ophthalmology, Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Bern 3010, Switzerland.
  • Fauser S; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland.
  • Plodinec M; Biozentrum and the Swiss Nanoscience Institute, University of Basel, Basel 4056, Switzerland. Electronic address: marija.plodinec@unibas.ch.
  • Iacone R; Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel 4070, Switzerland. Electronic address: roberto.iacone47@gmail.com.
EBioMedicine ; 27: 258-274, 2018 Jan.
Article en En | MEDLINE | ID: mdl-29269042
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Polaridad Celular / Epitelio Pigmentado de la Retina / Serina Peptidasa A1 que Requiere Temperaturas Altas / Degeneración Macular / Modelos Biológicos Idioma: En Revista: EBioMedicine Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tubulina (Proteína) / Polaridad Celular / Epitelio Pigmentado de la Retina / Serina Peptidasa A1 que Requiere Temperaturas Altas / Degeneración Macular / Modelos Biológicos Idioma: En Revista: EBioMedicine Año: 2018 Tipo del documento: Article