New 2-arylbenzofurans from the root bark of Artocarpus gomezianus and their α-glucosidase inhibitory activity.
Nat Prod Res
; 33(10): 1436-1441, 2019 May.
Article
en En
| MEDLINE
| ID: mdl-29281901
ABSTRACT
Two new 2-arylbenzofurans, namely 13-O-methyllakoochin B (1) and artogomezianin (2), were isolated from the root bark of Artocarpus gomezianus, along with six known compounds (3-8). The structures of new compounds were determined by spectroscopic and chemical methods. All of the isolates were evaluated for their α-glucosidase inhibitory activity. Artogomezianin (2) and lakoochin A (3) exhibited strong α-glucosidase inhibitory activity with IC50 values of 18.25 and 26.19 µM, respectively, as compared with the positive control acarbose.
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Base de datos:
MEDLINE
Asunto principal:
Benzofuranos
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Extractos Vegetales
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Raíces de Plantas
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Corteza de la Planta
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Artocarpus
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Inhibidores de Glicósido Hidrolasas
Idioma:
En
Revista:
Nat Prod Res
Año:
2019
Tipo del documento:
Article