Momordica charantia polysaccharides ameliorate oxidative stress, inflammation, and apoptosis in ethanol-induced gastritis in mucosa through NF-kB signaling pathway inhibition.

Raish, Mohammad; Ahmad, Ajaz; Ansari, Mushtaq Ahmad; Alkharfy, Khalid M; Aljenoobi, Fahad I; Jan, Basit L; Al-Mohizea, Abdullah M; Khan, Altaf; Ali, Naushad

Raish, Mohammad; Ahmad, Ajaz; Ansari, Mushtaq Ahmad; Alkharfy, Khalid M; Aljenoobi, Fahad I; Jan, Basit L; Al-Mohizea, Abdullah M; Khan, Altaf; Ali, Naushad.

Afiliación

Raish M; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: mraish@ksu.edu.sa.
Ahmad A; Department Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ansari MA; Department Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Alkharfy KM; Department Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Aljenoobi FI; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Jan BL; Department Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Al-Mohizea AM; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Khan A; Department Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Ali N; Quality Assurance Unit, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

Int J Biol Macromol ; 111: 193-199, 2018 May.

Article en En | MEDLINE | ID: mdl-29307809

Asunto(s)

Gastritis/tratamiento farmacológico; Inflamación/tratamiento farmacológico; Momordica charantia/química; Polisacáridos/administración & dosificación; Animales; Apoptosis/efectos de los fármacos; Citocinas/genética; Etanol/toxicidad; Gastritis/inducido químicamente; Gastritis/genética; Gastritis/patología; Expresión Génica/efectos de los fármacos; Humanos; Inflamación/inducido químicamente; Inflamación/genética; Inflamación/patología; Interleucina-6/genética; Peroxidación de Lípido/efectos de los fármacos; FN-kappa B/genética; Estrés Oxidativo/efectos de los fármacos; Peroxidasa/genética; Polisacáridos/química; Ratas; Transducción de Señal/efectos de los fármacos

Palabras clave

Apoptosis; Gastric injury; Momordica charantia polysaccharide; Oxidative stress

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Polisacáridos / Momordica charantia / Gastritis / Inflamación Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article

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