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Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles.
Burk, Oliver; Kuzikov, Maria; Kronenberger, Thales; Jeske, Judith; Keminer, Oliver; Thasler, Wolfgang E; Schwab, Matthias; Wrenger, Carsten; Windshügel, Björn.
Afiliación
  • Burk O; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany. oliver.burk@ikp-stuttgart.de.
  • Kuzikov M; University of Tübingen, Tübingen, Germany. oliver.burk@ikp-stuttgart.de.
  • Kronenberger T; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Schnackenburgallee 114, 22525, Hamburg, Germany.
  • Jeske J; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Schnackenburgallee 114, 22525, Hamburg, Germany.
  • Keminer O; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Thasler WE; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
  • Schwab M; University of Tübingen, Tübingen, Germany.
  • Wrenger C; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Schnackenburgallee 114, 22525, Hamburg, Germany.
  • Windshügel B; Department of General, Visceral, Transplantation, and Vascular Surgery, University of Munich, Campus Grosshadern, Munich, Germany.
Arch Toxicol ; 92(4): 1435-1451, 2018 Apr.
Article en En | MEDLINE | ID: mdl-29356861

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Sulfonamidas / Tacrolimus / Hepatocitos / Receptor X de Pregnano Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Arch Toxicol Año: 2018 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Sulfonamidas / Tacrolimus / Hepatocitos / Receptor X de Pregnano Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Arch Toxicol Año: 2018 Tipo del documento: Article