Chrysophanol demonstrates anti-inflammatory properties in LPS-primed RAW 264.7 macrophages through activating PPAR-Î³.

Wen, Quan; Mei, Liyan; Ye, Sen; Liu, Xia; Xu, Qin; Miao, Jifei; Du, Shaohui; Chen, Dongfeng; Li, Chun; Li, Hui

Wen, Quan; Mei, Liyan; Ye, Sen; Liu, Xia; Xu, Qin; Miao, Jifei; Du, Shaohui; Chen, Dongfeng; Li, Chun; Li, Hui.

Afiliación

Wen Q; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Mei L; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Ye S; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Liu X; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Xu Q; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Miao J; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Du S; Shenzhen Affliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Chen D; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Li C; School of Nursing Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Li H; School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. Electronic address: lihui@gzucm.edu.cn.

Int Immunopharmacol ; 56: 90-97, 2018 Mar.

Article en En | MEDLINE | ID: mdl-29367091

Asunto(s)

Antraquinonas/farmacología; Antiinflamatorios/farmacología; Macrófagos/inmunología; PPAR gamma/metabolismo; Sepsis/tratamiento farmacológico; Anilidas/farmacología; Animales; Interleucina-1beta/genética; Interleucina-1beta/metabolismo; Lipopolisacáridos/inmunología; Macrófagos/efectos de los fármacos; Ratones; FN-kappa B/metabolismo; Óxido Nítrico Sintasa de Tipo II/genética; Óxido Nítrico Sintasa de Tipo II/metabolismo; Células RAW 264.7; Rheum/inmunología; Rizoma; Transducción de Señal; Factor de Necrosis Tumoral alfa/genética; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Anti-inflammatory; Chrysophanol; NF-κB p65; PPAR-Î³; Sepsis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Antraquinonas / Sepsis / PPAR gamma / Macrófagos / Antiinflamatorios Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2018 Tipo del documento: Article

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