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Biological macromolecules for ophthalmic drug delivery to treat ocular diseases.
Krishnaswami, Venkateshwaran; Kandasamy, Ruckmani; Alagarsamy, Shanmugarathinam; Palanisamy, Rajaguru; Natesan, Subramanian.
Afiliación
  • Krishnaswami V; Department of Pharmaceutical Technology, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India; National Facility on Bioactive Peptides from Milk, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India.
  • Kandasamy R; Department of Pharmaceutical Technology, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India; National Facility for Drug Development, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India; National Facility on
  • Alagarsamy S; Department of Pharmaceutical Technology, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India.
  • Palanisamy R; Department of Biotechnology, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India.
  • Natesan S; Department of Pharmaceutical Technology, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India; National Facility for Drug Development, University College of Engineering, BIT Campus, Anna University, Tiruchirappalli, Tamilnadu, India; National Facility on
Int J Biol Macromol ; 110: 7-16, 2018 Apr 15.
Article en En | MEDLINE | ID: mdl-29378276
ABSTRACT
Development of newer drug carrier systems by the researchers has resulted in numerous breakthroughs in the development and manufacturing of ocular products. The ocular bioavailability of drugs at the posterior segment of the eye is a challenging task in the present scenario. Naturally derived macromolecular carriers are widely used to increase the efficacy of ocular drugs. They provide enhanced corneal permeability and retention effect at the surface of cornea for a prolonged period of time. In this regimen the present review focuses towards the major ocular diseases and their prevalence and development of efficient drug carrier systems utilizing various naturally derived macromolecules for improved delivery of drugs to treat ocular diseases.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Portadores de Fármacos / Oftalmopatías Tipo de estudio: Risk_factors_studies Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Portadores de Fármacos / Oftalmopatías Tipo de estudio: Risk_factors_studies Idioma: En Revista: Int J Biol Macromol Año: 2018 Tipo del documento: Article