Silencing Lin28 promotes apoptosis in colorectal cancer cells by upregulating let­7c targeting of antiapoptotic BCL2L1.

Zhang, Haogang; Zong, Yaguang; Qiu, Gongcai; Jia, Ruichun; Xu, Xunzheng; Wang, Fujing; Wu, Dequan

Silencing Lin28 promotes apoptosis in colorectal cancer cells by upregulating let7c targeting of antiapoptotic BCL2L1.

Zhang, Haogang; Zong, Yaguang; Qiu, Gongcai; Jia, Ruichun; Xu, Xunzheng; Wang, Fujing; Wu, Dequan.

Afiliación

Zhang H; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.
Zong Y; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.
Qiu G; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.
Jia R; Department of Blood Transfusion, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.
Xu X; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.
Wang F; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.
Wu D; Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150081, P.R. China.

Mol Med Rep ; 17(4): 5143-5149, 2018 04.

Article en En | MEDLINE | ID: mdl-29393430

Asunto(s)

Apoptosis/genética; Neoplasias Colorrectales/genética; Regulación Neoplásica de la Expresión Génica; Silenciador del Gen; MicroARNs/genética; Proteínas de Unión al ARN/genética; Proteína bcl-X/genética; Adulto; Anciano; Caspasa 3/metabolismo; Línea Celular Tumoral; Neoplasias Colorrectales/metabolismo; Femenino; Humanos; Masculino; Persona de Mediana Edad; Procesamiento Postranscripcional del ARN; Regulación hacia Arriba

Palabras clave

colorectal cancer; Lin28; let-7; apoptosis; Bcl-2-like

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Regulación Neoplásica de la Expresión Génica / Proteínas de Unión al ARN / Apoptosis / Silenciador del Gen / MicroARNs / Proteína bcl-X Idioma: En Revista: Mol Med Rep Año: 2018 Tipo del documento: Article

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