Mastectomy patterns, but not rates, are changing in the treatment of early breast cancer. Experience of a single European institution on 2315 consecutive patients.
Breast
; 39: 1-7, 2018 Jun.
Article
en En
| MEDLINE
| ID: mdl-29454174
ABSTRACT
BACKGROUND:
Recent literature reports that rates of mastectomy are increasing in early breast cancer. However, data from European institutions are limited and revealed conflicting results. We report on 15-year trends of mastectomy, mastectomy plus immediate reconstruction and contralateral prophylactic mastectomy (CPM) at an academic institution.METHODS:
We identified women diagnosed with unilateral early breast cancer at stage 0-IIa, with tumour sizeâ¯≤â¯4â¯cm, between 2002 and 2016. Trends were assessed using the Cochrane-Armitage test. Multivariable logistic regression was used to identify factors associated with receipt of mastectomy plus immediate reconstruction.RESULTS:
A total of 2315 patients were identified. Of them, 65.7% underwent breast conserving surgery (BCS), while 34.3% underwent mastectomy as upfront surgery. Two point four per cent also received CPM. Immediate reconstruction was performed in 36.0% of patients receiving mastectomy. There was no change in trends of mastectomy over the 15 years studied (pâ¯=â¯0.69), as well as in trends of patients undergoing CPM (pâ¯=â¯0.44). In contrast, rates of immediate reconstruction rose significantly over the study period (from 12.2% in 2002 to 62.7% in 2016, pâ¯<â¯0.0001). Women were more likely to receive mastectomy plus immediate reconstruction if they were aged 50 years or younger, or had tumours larger than 2â¯cm, or had non-invasive carcinoma.CONCLUSIONS:
Our study suggests that rates of both mastectomy and CPM in early breast cancer are not increasing, while use of immediate reconstruction is on the rise.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Mastectomía Segmentaria
/
Mamoplastia
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Neoplasias de Mama Unilaterales
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Mastectomía Profiláctica
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Mastectomía
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
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Screening_studies
Idioma:
En
Revista:
Breast
Asunto de la revista:
ENDOCRINOLOGIA
/
NEOPLASIAS
Año:
2018
Tipo del documento:
Article