Cell wall enrichment unveils proteomic changes in the cell wall during treatment of Mycobacterium smegmatis with sub-lethal concentrations of rifampicin.

Hermann, Clemens; Giddey, Alexander D; Nel, Andrew J M; Soares, Nelson C; Blackburn, Jonathan M

Hermann, Clemens; Giddey, Alexander D; Nel, Andrew J M; Soares, Nelson C; Blackburn, Jonathan M.

Afiliación

Hermann C; Department of Integrative Biomedical Sciences, Institute of Infectious Disease & Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road Observatory, Cape Town 7925, South Africa.
Giddey AD; Department of Integrative Biomedical Sciences, Institute of Infectious Disease & Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road Observatory, Cape Town 7925, South Africa.
Nel AJM; Department of Integrative Biomedical Sciences, Institute of Infectious Disease & Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road Observatory, Cape Town 7925, South Africa.
Soares NC; Department of Integrative Biomedical Sciences, Institute of Infectious Disease & Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road Observatory, Cape Town 7925, South Africa.
Blackburn JM; Department of Integrative Biomedical Sciences, Institute of Infectious Disease & Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road Observatory, Cape Town 7925, South Africa. Electronic address: jonathan.blackburn@uct.ac.za.

J Proteomics ; 191: 166-179, 2019 01 16.

Article en En | MEDLINE | ID: mdl-29466714

Asunto(s)

Pared Celular/química; Mycobacterium smegmatis/efectos de los fármacos; Proteoma/metabolismo; Rifampin/farmacología; Transportadoras de Casetes de Unión a ATP/metabolismo; Proteínas Bacterianas/análisis; Proteínas Bacterianas/efectos de los fármacos; Pared Celular/efectos de los fármacos; Proteoma/efectos de los fármacos; Proteómica/métodos; Factores de Virulencia/metabolismo

Palabras clave

Antibiotics; Cell wall proteomics; Mass spectrometry; Mycobacteria; Tuberculosis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rifampin / Pared Celular / Mycobacterium smegmatis / Proteoma Tipo de estudio: Prognostic_studies Idioma: En Revista: J Proteomics Asunto de la revista: BIOQUIMICA Año: 2019 Tipo del documento: Article

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