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Directed evolution of SIRT6 for improved deacylation and glucose homeostasis maintenance.
Gertman, Or; Omer, Dotan; Hendler, Adi; Stein, Daniel; Onn, Lior; Khukhin, Yana; Portillo, Miguel; Zarivach, Raz; Cohen, Haim Y; Toiber, Debra; Aharoni, Amir.
Afiliación
  • Gertman O; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Omer D; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Hendler A; Smartzyme Innovation LTD, Ilan Ramon, Science Park-Ness Ziona, Ness Ziona, Israel.
  • Stein D; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Onn L; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Khukhin Y; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Portillo M; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Zarivach R; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Cohen HY; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
  • Toiber D; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, 5290002, Israel.
  • Aharoni A; Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, 84105, Israel.
Sci Rep ; 8(1): 3538, 2018 02 23.
Article en En | MEDLINE | ID: mdl-29476161

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Histonas / Ingeniería de Proteínas / Factor de Necrosis Tumoral alfa / Evolución Molecular Dirigida / Sirtuinas / Glucosa Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Histonas / Ingeniería de Proteínas / Factor de Necrosis Tumoral alfa / Evolución Molecular Dirigida / Sirtuinas / Glucosa Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article