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In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.
Cheng, Ran; Mori, Wakana; Ma, Longle; Alhouayek, Mireille; Hatori, Akiko; Zhang, Yiding; Ogasawara, Daisuke; Yuan, Gengyang; Chen, Zhen; Zhang, Xiaofei; Shi, Hang; Yamasaki, Tomoteru; Xie, Lin; Kumata, Katsushi; Fujinaga, Masayuki; Nagai, Yuji; Minamimoto, Takafumi; Svensson, Mona; Wang, Lu; Du, Yunfei; Ondrechen, Mary Jo; Vasdev, Neil; Cravatt, Benjamin F; Fowler, Christopher; Zhang, Ming-Rong; Liang, Steven H.
Afiliación
  • Cheng R; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Mori W; School of Pharmaceutical Science and Technology , Tianjin University , 92 Weijin Road, Nankai District , Tianjin 300072 , China.
  • Ma L; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Alhouayek M; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Hatori A; Department of Pharmacology and Clinical Neuroscience , Umeå University , SE-901 87 Umeå , Sweden.
  • Zhang Y; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Ogasawara D; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Yuan G; The Skaggs Institute for Chemical Biology and Department of Chemical Physiology , The Scripps Research Institute , SR107 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.
  • Chen Z; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Zhang X; Department of Chemistry and Chemical Biology , Northeastern University , 360 Huntington Avenue , Boston , Massachusetts 02115 , United States.
  • Shi H; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Yamasaki T; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Xie L; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Kumata K; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Fujinaga M; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Nagai Y; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Minamimoto T; Department of Radiopharmaceuticals Development , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Svensson M; Department of Functional Brain Imaging Research , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Wang L; Department of Functional Brain Imaging Research , National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology , Chiba 263-8555 , Japan.
  • Du Y; Department of Pharmacology and Clinical Neuroscience , Umeå University , SE-901 87 Umeå , Sweden.
  • Ondrechen MJ; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Vasdev N; School of Pharmaceutical Science and Technology , Tianjin University , 92 Weijin Road, Nankai District , Tianjin 300072 , China.
  • Cravatt BF; Department of Chemistry and Chemical Biology , Northeastern University , 360 Huntington Avenue , Boston , Massachusetts 02115 , United States.
  • Fowler C; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
  • Zhang MR; The Skaggs Institute for Chemical Biology and Department of Chemical Physiology , The Scripps Research Institute , SR107 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.
  • Liang SH; Department of Pharmacology and Clinical Neuroscience , Umeå University , SE-901 87 Umeå , Sweden.
J Med Chem ; 61(6): 2278-2291, 2018 03 22.
Article en En | MEDLINE | ID: mdl-29481079

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Azetidinas / Radiofármacos / Tomografía de Emisión de Positrones / Monoacilglicerol Lipasas Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Azetidinas / Radiofármacos / Tomografía de Emisión de Positrones / Monoacilglicerol Lipasas Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article