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Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation.
Hammill, Jared T; Bhasin, Deepak; Scott, Daniel C; Min, Jaeki; Chen, Yizhe; Lu, Yan; Yang, Lei; Kim, Ho Shin; Connelly, Michele C; Hammill, Courtney; Holbrook, Gloria; Jeffries, Cynthia; Singh, Bhuvanesh; Schulman, Brenda A; Guy, R Kiplin.
Afiliación
  • Hammill JT; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Bhasin D; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Scott DC; Howard Hughes Medical Institute , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Min J; Department of Structural Biology , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Chen Y; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Lu Y; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Yang L; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Kim HS; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Connelly MC; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Hammill C; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Holbrook G; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Jeffries C; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Singh B; Department of Chemical Biology and Theraputics , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
  • Schulman BA; Department of Surgery, Laboratory of Epithelial Cancer Biology , Memorial Sloan Kettering Cancer Center , New York , New York , 10065 United States.
  • Guy RK; Howard Hughes Medical Institute , St. Jude Children's Research Hospital , Memphis , Tennessee 38105 United States.
J Med Chem ; 61(7): 2694-2706, 2018 04 12.
Article en En | MEDLINE | ID: mdl-29547693
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Cullin / Antineoplásicos Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Cullin / Antineoplásicos Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article