Final safety, tolerability, and seizure outcomes in patients with focal epilepsy treated with adjunctive perampanel for up to 4 years in an open-label extension of phase III randomized trials: Study 307.

Krauss, Gregory L; Perucca, Emilio; Kwan, Patrick; Ben-Menachem, Elinor; Wang, Xue-Feng; Shih, Jerry J; Patten, Anna; Yang, Haichen; Williams, Betsy; Laurenza, Antonio

Krauss, Gregory L; Perucca, Emilio; Kwan, Patrick; Ben-Menachem, Elinor; Wang, Xue-Feng; Shih, Jerry J; Patten, Anna; Yang, Haichen; Williams, Betsy; Laurenza, Antonio.

Afiliación

Krauss GL; Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
Perucca E; IRCCS Mondino Foundation, Pavia, Italy.
Kwan P; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Ben-Menachem E; Royal Melbourne Hospital, University of Melbourne, Parkville, Vic., Australia.
Wang XF; Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
Shih JJ; Sahlgrenska Academy, Gothenburg, Sweden.
Patten A; Chongqing Key Laboratory of Neurology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yang H; Department of Neurosciences, UCSD School of Medicine, La Jolla, CA, USA.
Williams B; Department of Biostatistics, Eisai Ltd., Hatfield, UK.
Laurenza A; Former Employee of Eisai Inc., Woodcliff Lake, NJ, USA.

Epilepsia ; 59(4): 866-876, 2018 04.

Article en En | MEDLINE | ID: mdl-29574701

Asunto(s)

Anticonvulsivantes/administración & dosificación; Epilepsias Parciales/diagnóstico; Epilepsias Parciales/tratamiento farmacológico; Piridonas/administración & dosificación; Convulsiones/diagnóstico; Convulsiones/tratamiento farmacológico; Anticonvulsivantes/efectos adversos; Mareo/inducido químicamente; Método Doble Ciego; Esquema de Medicación; Quimioterapia Combinada; Femenino; Estudios de Seguimiento; Cefalea/inducido químicamente; Humanos; Nitrilos; Piridonas/efectos adversos; Factores de Tiempo; Resultado del Tratamiento

Palabras clave

antiepileptic drugs; focal seizures; long-term safety/tolerability; perampanel; secondarily generalized seizures

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piridonas / Convulsiones / Epilepsias Parciales / Anticonvulsivantes Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Epilepsia Año: 2018 Tipo del documento: Article

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