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The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.
Mead, Timothy J; McCulloch, Daniel R; Ho, Jason C; Du, Yaoyao; Adams, Sheila M; Birk, David E; Apte, Suneel S.
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  • Mead TJ; Department of Biomedical Engineering and the Orthopaedic and Rheumatologic Institute, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • McCulloch DR; Department of Biomedical Engineering and the Orthopaedic and Rheumatologic Institute, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Ho JC; Department of Biomedical Engineering and the Orthopaedic and Rheumatologic Institute, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Du Y; Department of Orthopaedic Surgery and the Orthopaedic and Rheumatology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
  • Adams SM; Department of Biomedical Engineering and the Orthopaedic and Rheumatologic Institute, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Birk DE; Departments of Molecular Pharmacology and Physiology and Orthopaedics and Sports Medicine, University of South Florida, Morsani College of Medicine, Tampa, Florida, USA.
  • Apte SS; Departments of Molecular Pharmacology and Physiology and Orthopaedics and Sports Medicine, University of South Florida, Morsani College of Medicine, Tampa, Florida, USA.
JCI Insight ; 3(7)2018 04 05.
Article en En | MEDLINE | ID: mdl-29618652
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoartritis / Tendones / Osificación Heterotópica / Proteínas ADAMTS / Proteína ADAMTS7 Idioma: En Revista: JCI Insight Año: 2018 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoartritis / Tendones / Osificación Heterotópica / Proteínas ADAMTS / Proteína ADAMTS7 Idioma: En Revista: JCI Insight Año: 2018 Tipo del documento: Article