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Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice.
Richter, Wolfgang F; Christianson, Gregory J; Frances, Nicolas; Grimm, Hans Peter; Proetzel, Gabriele; Roopenian, Derry C.
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  • Richter WF; a Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , Grenzacherstrasse , Basel , Switzerland.
  • Christianson GJ; b The Jackson Laboratory , Bar Harbor , ME USA.
  • Frances N; a Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , Grenzacherstrasse , Basel , Switzerland.
  • Grimm HP; a Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd. , Grenzacherstrasse , Basel , Switzerland.
  • Proetzel G; b The Jackson Laboratory , Bar Harbor , ME USA.
  • Roopenian DC; b The Jackson Laboratory , Bar Harbor , ME USA.
MAbs ; 10(5): 803-813, 2018 07.
Article en En | MEDLINE | ID: mdl-29621428
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Receptores Fc / Antígenos de Histocompatibilidad Clase I / Anticuerpos Monoclonales Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Receptores Fc / Antígenos de Histocompatibilidad Clase I / Anticuerpos Monoclonales Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article