Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-&#954;B and stimulation of PI3K/AKT.

Liu, Jingjing; Zhang, Zhuanzhuan; Guo, Qi; Dong, Yanhong; Zhao, Qipeng; Ma, Xueqin

Syringin prevents bone loss in ovariectomized mice via TRAF6 mediated inhibition of NF-κB and stimulation of PI3K/AKT.

Liu, Jingjing; Zhang, Zhuanzhuan; Guo, Qi; Dong, Yanhong; Zhao, Qipeng; Ma, Xueqin.

Afiliación

Liu J; Department of Pharmaceutical analysis, School of Pharmacy, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China.
Zhang Z; Department of Pharmaceutical analysis, School of Pharmacy, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China.
Guo Q; Department of Pharmaceutical analysis, School of Pharmacy, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China.
Dong Y; Department of Pharmaceutical analysis, School of Pharmacy, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China.
Zhao Q; Department of Pharmaceutical analysis, School of Pharmacy, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, 692 Shenli Street, Yinchuan 750004, China.
Ma X; Department of Pharmaceutical analysis, School of Pharmacy, Ningxia Medical University, 1160 Shenli Street, Yinchuan 750004, China; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, 692 Shenli Street, Yinchuan 750004, China. Electronic address: ma

Phytomedicine ; 42: 43-50, 2018 Mar 15.

Article en En | MEDLINE | ID: mdl-29655696

Asunto(s)

Glucósidos/farmacología; FN-kappa B/metabolismo; Osteoporosis/tratamiento farmacológico; Fenilpropionatos/farmacología; Factor 6 Asociado a Receptor de TNF/metabolismo; Animales; Densidad Ósea/efectos de los fármacos; Enfermedades Óseas Metabólicas; Catepsina K/metabolismo; Femenino; Ratones Endogámicos ICR; Osteogénesis/efectos de los fármacos; Osteoporosis/metabolismo; Osteoprotegerina/metabolismo; Ovariectomía; Fosfatidilinositol 3-Quinasas/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Fosfatasa Ácida Tartratorresistente/metabolismo

Palabras clave

Antiosteoporotic; NF-κB; Ovariectomized mice; Syringin; TRAF6

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoporosis / Fenilpropionatos / FN-kappa B / Factor 6 Asociado a Receptor de TNF / Glucósidos Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2018 Tipo del documento: Article

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