[Analysis and dynamic observation of inhaled and food allergens for people in Pearl River Delta].

ABSTRACT

Objective:To investigate the distribution of allergens in patients with suspected allergic diseases in Pearl River Delta, analysis the changes of allergens with seasons and years, and provide clinical references for management strategies with regional character.Method:Patients from 9 hospitals in Pearl River Delta, with suspected clinical symptoms and signs of allergic disease, were given serum specific IgE test from September 2012 to April 2016. The positive rate was compared with genders, ages, the dynamic changes of seasons, and years.Result:In 30 003 patients, the positive rate of dust mites, house dust, tree, mugwort, mold, animal dander were 39.3%, 26.1%, 16.9%, 26.1%, 9.0%, 6.0% respectively. In 22748 patients, the positive rate of egg, milk, fish, seafood, meats, fruits, nuts were 13.5%, 14.5%, 10.3%, 14.5%, 10.9%, 15.4%, 10.9%. The positive rate of female patients are higher than male patients in both inhaled and food allergens (P< 0.01). The positive rate of minor group was obviously higher than that of the adult group (P< 0.01). The highest positive rate of dust mite, mold, animal dander, egg, fish occurs in the spring, while trees, mugwort, house dust, milk, seafood, meats, fruits, nuts in summer (P< 0.01). There was an upward trend in the positive rate of dust mite, while the positive rate of house dust, mugwort, mold, egg, milk was on the decline, and positive rate of other allergens changed in volatility from 2013 to 2015 (P< 0.01).Conclusion:The dust mites, house dust, seafood and fruits were the main allergens in Pearl River Delta and should be the key for prevention and treatment of allergic diseases. More attention should be paid to the patients of allergic diseases of minors and major seasonal allergens in clinical prevention and treatment. The changes of allergens with the years and dietary habit in local area for the prevention and control of allergic diseases are also not allowed to be ignored.