Calcifying Odontogenic Cyst Associated With Dentigerous Cyst in a 15-Year-Old Girl.
Int J Surg Pathol
; 26(8): 758-765, 2018 Dec.
Article
en En
| MEDLINE
| ID: mdl-29890883
ABSTRACT
Calcifying odontogenic cyst (COC) is a rare odontogenic cyst with ameloblastic epithelial lining containing clusters of ghost cells. COCs have been described in association with several odontogenic tumors, more commonly odontomas and rarely with dentigerous cyst (DC). In this article, we describe a case of COC associated with DC in a 15-year-old girl, who presented with a swelling on the right middle third of the face, producing facial asymmetry. Panoramic radiography showed a well-circumscribed, corticated, and unilocular radiolucency at the level of the right maxillary sinus, involving 2 unerupted premolars. The lesion was enucleated and histologically revealed a COC associated with DC, which presented mucous metaplasia. Immunohistochemical reactions were performed to better illustrate this rare synchronous occurrence of COC and DC, showing positivity for CK5, CK14, CK19, and p63 in both lesions. CK18 was negative in COC, and Bcl-2 was negative in DC. Periodic acid Schiff highlighted the mucous cells in the DC lining.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Quiste Dentígero
/
Neoplasias Maxilares
/
Biomarcadores de Tumor
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Quiste Odontogénico Calcificado
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
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Risk_factors_studies
Idioma:
En
Revista:
Int J Surg Pathol
Asunto de la revista:
PATOLOGIA
Año:
2018
Tipo del documento:
Article