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Evaluating Antimicrobial Use and Spectrum of Activity in Ontario Hospitals: Feasibility of a Multicentered Point Prevalence Study.
Leung, Valerie; Li, Michael; Wu, Julie Hui-Chih; Langford, Bradley; Zvonar, Rosemary; Powis, Jeff; Longpre, Julie; Béïque, Lizanne; Gill, Suzanne; Ho, Grace; Garber, Gary.
Afiliación
  • Leung V; Infection Prevention and Control, Public Health Ontario.
  • Li M; Leslie Dan Faculty of Pharmacy, University of Toronto.
  • Wu JH; Infection Prevention and Control, Public Health Ontario.
  • Langford B; Infection Prevention and Control, Public Health Ontario.
  • Zvonar R; Department of Pharmacy, The Ottawa Hospital and Ottawa Hospital Research Institute.
  • Powis J; Department of Medicine, Michael Garron Hospital, Toronto.
  • Longpre J; Department of Pharmacy, Cornwall Community Hospital.
  • Béïque L; Department of Pharmacy, The Ottawa Hospital and Ottawa Hospital Research Institute.
  • Gill S; Department of Pharmaceutial Services, Michael Garron Hospital, Toronto.
  • Ho G; Department of Pharmaceutial Services, Michael Garron Hospital, Toronto.
  • Garber G; Division of Infectious Diseases, The Ottawa Hospital.
Open Forum Infect Dis ; 5(6): ofy110, 2018 Jun.
Article en En | MEDLINE | ID: mdl-29977965
ABSTRACT

BACKGROUND:

Antimicrobial stewardship, a key component of an overall strategy to address antimicrobial resistance, has been recognized as a global priority. The ability to track and benchmark antimicrobial use (AMU) is critical to advancing stewardship from an organizational and provincial perspective. As there are few comprehensive systems in Canada that allow for benchmarking, Public Health Ontario conducted a pilot in 2016/2017 to assess the feasibility of using a point prevalence methodology as the basis of a province-wide AMU surveillance program.

METHODS:

Three acute care hospitals of differing sizes in Ontario, Canada, participated. Adults admitted to inpatient acute care beds on the survey date were eligible for inclusion; a sample size of 170 per hospital was targeted, and data were collected for the 24-hour period before and including the survey date. Debrief sessions at each site were used to gather feedback about the process. Prevalence of AMU and the Antimicrobial Spectrum Index (ASI) was reported for each hospital and by indication per patient case.

RESULTS:

Participants identified required improvements for scalability including streamlining ethics, data sharing processes, and enhancing the ability to compare with peer organizations at a provincial level. Of 457 patients, 172 (38%) were receiving at least 1 antimicrobial agent. Beta-lactam/beta-lactamase inhibitors were the most common (18%). The overall mean ASI per patient was 6.59; most cases were for treatment of infection (84%).

CONCLUSIONS:

This pilot identified factors and features required for a scalable provincial AMU surveillance program; future efforts should harmonize administrative processes and enable interfacility benchmarking.
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Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Open Forum Infect Dis Año: 2018 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Open Forum Infect Dis Año: 2018 Tipo del documento: Article