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Discovery of novel spiro[chromane-2,4'-piperidine] derivatives as potent and orally bioavailable G-protein-coupled receptor 119 agonists.
Koshizawa, Tomoaki; Morimoto, Toshiharu; Watanabe, Gen; Fukuda, Tomoaki; Yamasaki, Nao; Hagita, Sumihiko; Sawada, Yoshikazu; Okuda, Ayumu; Shibuya, Kimiyuki; Ohgiya, Tadaaki.
Afiliación
  • Koshizawa T; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp.
  • Morimoto T; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Watanabe G; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Fukuda T; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Yamasaki N; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Hagita S; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Sawada Y; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Okuda A; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Shibuya K; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
  • Ohgiya T; Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD, 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan.
Bioorg Med Chem Lett ; 28(19): 3236-3241, 2018 10 15.
Article en En | MEDLINE | ID: mdl-30145005
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piperidinas / Cromanos / Proteínas de Unión al GTP Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piperidinas / Cromanos / Proteínas de Unión al GTP Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article