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Synthesis and Characterization of the Selective, Reversible PKCß Inhibitor (9 S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9 H,18 H-5,21:12,17-dimethenodibenzo[ e,k]pyrrolo[3,4- h][1,4,13]oxadiazacyclohexadecine-18,20(19 H)-dione, Ruboxistaurin (LY333531).
Lewin, Anita H; Brieaddy, Larry; Deschamps, Jeffrey R; Imler, Gregory H; Mascarella, S Wayne; Reddy, P Anantha; Carroll, F Ivy.
Afiliación
  • Lewin AH; Research Triangle Institute , P.O. Box 12194, Research Triangle Park , North Carolina 27709 , United States.
  • Brieaddy L; Research Triangle Institute , P.O. Box 12194, Research Triangle Park , North Carolina 27709 , United States.
  • Deschamps JR; Laboratory for Biosensors and Biomaterials, Center for Biomolecular Science and Engineering , United States Naval Research Laboratory (NRL) , Washington , D.C. 20375 , United States.
  • Imler GH; Laboratory for Biosensors and Biomaterials, Center for Biomolecular Science and Engineering , United States Naval Research Laboratory (NRL) , Washington , D.C. 20375 , United States.
  • Mascarella SW; Research Triangle Institute , P.O. Box 12194, Research Triangle Park , North Carolina 27709 , United States.
  • Reddy PA; Research Triangle Institute , P.O. Box 12194, Research Triangle Park , North Carolina 27709 , United States.
  • Carroll FI; Research Triangle Institute , P.O. Box 12194, Research Triangle Park , North Carolina 27709 , United States.
ACS Chem Neurosci ; 10(1): 246-251, 2019 01 16.
Article en En | MEDLINE | ID: mdl-30156829

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Química Farmacéutica / Inhibidores Enzimáticos / Proteína Quinasa C beta / Indoles / Maleimidas Idioma: En Revista: ACS Chem Neurosci Año: 2019 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Química Farmacéutica / Inhibidores Enzimáticos / Proteína Quinasa C beta / Indoles / Maleimidas Idioma: En Revista: ACS Chem Neurosci Año: 2019 Tipo del documento: Article