Sensory nerves mediate spontaneous behaviors in addition to inflammation in a murine model of psoriasis.

Kodji, Xenia; Arkless, Kate L; Kee, Zizheng; Cleary, Simon J; Aubdool, Aisah A; Evans, Elizabeth; Caton, Paul; Pitchford, Simon C; Brain, Susan D

Kodji, Xenia; Arkless, Kate L; Kee, Zizheng; Cleary, Simon J; Aubdool, Aisah A; Evans, Elizabeth; Caton, Paul; Pitchford, Simon C; Brain, Susan D.

Afiliación

Kodji X; British Heart Foundation (BHF) Cardiovascular Centre of Research Excellence, Vascular Biology and Inflammation Section, King's College London, London, United Kingdom.
Arkless KL; British Heart Foundation (BHF) Cardiovascular Centre of Research Excellence, Vascular Biology and Inflammation Section, King's College London, London, United Kingdom.
Kee Z; British Heart Foundation (BHF) Cardiovascular Centre of Research Excellence, Vascular Biology and Inflammation Section, King's College London, London, United Kingdom.
Cleary SJ; Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Aubdool AA; British Heart Foundation (BHF) Cardiovascular Centre of Research Excellence, Vascular Biology and Inflammation Section, King's College London, London, United Kingdom.
Evans E; Diabetes Research Group, Division of Diabetes and Nutritional Sciences, King's College London, London, United Kingdom.
Caton P; Diabetes Research Group, Division of Diabetes and Nutritional Sciences, King's College London, London, United Kingdom.
Pitchford SC; Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, United Kingdom.
Brain SD; British Heart Foundation (BHF) Cardiovascular Centre of Research Excellence, Vascular Biology and Inflammation Section, King's College London, London, United Kingdom.

FASEB J ; 33(2): 1578-1594, 2019 02.

Article en En | MEDLINE | ID: mdl-30204499

Asunto(s)

Inflamación/patología; Psoriasis/patología; Células Receptoras Sensoriales/patología; Animales; Péptido Relacionado con Gen de Calcitonina/metabolismo; Desnervación; Modelos Animales de Enfermedad; Diterpenos/farmacología; Imiquimod/farmacología; Inflamación/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Psoriasis/metabolismo; Especies de Nitrógeno Reactivo/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Células Receptoras Sensoriales/metabolismo; Piel/irrigación sanguínea; Piel/patología; Sustancia P/metabolismo; Canal Catiónico TRPA1/metabolismo; Canales Catiónicos TRPV/metabolismo

Palabras clave

TRP channels; macrophages; neuropeptides; oxidative stress; peroxynitrite

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Psoriasis / Células Receptoras Sensoriales / Inflamación Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2019 Tipo del documento: Article

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