Intracellular activation of complement C3 in Paneth cells improves repair of intestinal epithelia during acute injury.

Zhang, Jian; Ye, Jinning; Ren, Yufeng; Zuo, Jidong; Dai, Weigang; He, Yulong; Tan, Min; Song, Wu; Yuan, Yujie

Zhang, Jian; Ye, Jinning; Ren, Yufeng; Zuo, Jidong; Dai, Weigang; He, Yulong; Tan, Min; Song, Wu; Yuan, Yujie.

Afiliación

Zhang J; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.
Ye J; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.
Ren Y; Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, PR China.
Zuo J; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.
Dai W; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.
He Y; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.
Tan M; Center of Gastric Cancer, Sun Yat-sen University, Guangzhou 510080, PR China.
Song W; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.
Yuan Y; Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, PR China.

Immunotherapy ; 10(15): 1325-1336, 2018 11.

Article en En | MEDLINE | ID: mdl-30381988

Asunto(s)

Complemento C3/uso terapéutico; Enfermedades Gastrointestinales/terapia; Inmunoterapia/métodos; Mucosa Intestinal/efectos de los fármacos; Células de Paneth/efectos de los fármacos; Animales; Proliferación Celular; Células Cultivadas; Colon/cirugía; Activación de Complemento; Modelos Animales de Enfermedad; Femenino; Enfermedades Gastrointestinales/inmunología; Humanos; Mucosa Intestinal/fisiología; Espacio Intracelular; Ratones; Ratones Endogámicos C57BL; Células de Paneth/fisiología; Cicatrización de Heridas

Palabras clave

Paneth cells; abdominal infection; complement C3; gut epithelia; immunotherapy; intestinal injury; intracellular activation; lysozyme; repair and regeneration; survival

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Complemento C3 / Células de Paneth / Enfermedades Gastrointestinales / Inmunoterapia / Mucosa Intestinal Idioma: En Revista: Immunotherapy Asunto de la revista: ALERGIA E IMUNOLOGIA / TERAPEUTICA Año: 2018 Tipo del documento: Article

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