Isolated fetal echogenic bowel in a retrospective cohort: The role of infection screening.
Eur J Obstet Gynecol Reprod Biol
; 231: 136-141, 2018 Dec.
Article
en En
| MEDLINE
| ID: mdl-30388607
ABSTRACT
OBJECTIVE:
Fetal echogenic bowel (FEB) is an ultrasonographic marker of fetal infection. We aimed to determine the utility of infection screening when FEB is isolated. STUDYDESIGN:
Retrospective observational study of isolated FEB cases between 2006-2014. Infection screening included toxoplasmosis, rubella, syphilis, cytomegalovirus (CMV), herpes simplex virus and parvovirus B19. Fetal karyotyping, screening for cystic fibrosis (CF) and follow-up scans were also offered, according to international standards. Incidence of infection and 95% confidence interval (CI) were calculated.RESULTS:
148 patients with 154 fetuses were included. 4.7% of mothers developed acute infection four patients developed CMV infection (2.7%, 95% CI 1.1-6.9%), in two fetuses infection was confirmed with amniocentesis and pregnancies were terminated; Parvovirus B19 infection was detected in 2 patients (1.4%, 95% CI 0.4-5.0) and confirmed in one fetus, which developed anemia; there was one toxoplasmosis maternal infection (0.7%, 95% CI 0.1-3.8%) treated with spyramicin, whose fetus was not infected. Percentage of chromosomal/genetic abnormalities was 3.2%, CF 1.3%, intra-amniotic bleeding 1.3%, FGR 34% and other ultrasonographic abnormalities at follow-up scans 18%.CONCLUSIONS:
The association between isolated FEB and fetal infection is uncommon (1.9% in our population). CMV maternal infection screening is supported by our findings, whereas screening for other infections needs to be further investigated.Palabras clave
Texto completo:
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Base de datos:
MEDLINE
Asunto principal:
Complicaciones Infecciosas del Embarazo
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Infecciones por Citomegalovirus
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Intestino Ecogénico
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Risk_factors_studies
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Screening_studies
Idioma:
En
Revista:
Eur J Obstet Gynecol Reprod Biol
Año:
2018
Tipo del documento:
Article