A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes.

Ölander, Magnus; Wisniewski, Jacek R; Flörkemeier, Inken; Handin, Niklas; Urdzik, Jozef; Artursson, Per

Ölander, Magnus; Wisniewski, Jacek R; Flörkemeier, Inken; Handin, Niklas; Urdzik, Jozef; Artursson, Per.

Afiliación

Ölander M; Department of Pharmacy, Uppsala University, 75123, Uppsala, Sweden.
Wisniewski JR; Biochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
Flörkemeier I; Department of Pharmacy, Uppsala University, 75123, Uppsala, Sweden.
Handin N; Department of Pharmacy, Uppsala University, 75123, Uppsala, Sweden.
Urdzik J; Department of Surgical Sciences, Uppsala University, 75185, Uppsala, Sweden.
Artursson P; Department of Pharmacy and Science for Life Laboratory, Uppsala University, Uppsala, Sweden. per.artursson@farmaci.uu.se.

Arch Toxicol ; 93(3): 819-829, 2019 03.

Article en En | MEDLINE | ID: mdl-30560367

Asunto(s)

Criopreservación/métodos; Hepatocitos; Clorometilcetonas de Aminoácidos; Apoptosis; Inhibidores de Caspasas; Caspasas; Diferenciación Celular; Humanos; Hígado

Palabras clave

Apoptosis; Cellular stress; Cryopreservation; Hepatotoxicity; Human hepatocytes; Proteomics

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Criopreservación / Hepatocitos Idioma: En Revista: Arch Toxicol Año: 2019 Tipo del documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Criopreservación / Hepatocitos Idioma: En Revista: Arch Toxicol Año: 2019 Tipo del documento: Article