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Probing the Virtual Proteome to Identify Novel Disease Biomarkers.
Mosley, Jonathan D; Benson, Mark D; Smith, J Gustav; Melander, Olle; Ngo, Debby; Shaffer, Christian M; Ferguson, Jane F; Herzig, Matthew S; McCarty, Catherine A; Chute, Christopher G; Jarvik, Gail P; Gordon, Adam S; Palmer, Melody R; Crosslin, David R; Larson, Eric B; Carrell, David S; Kullo, Iftikhar J; Pacheco, Jennifer A; Peissig, Peggy L; Brilliant, Murray H; Kitchner, Terrie E; Linneman, James G; Namjou, Bahram; Williams, Marc S; Ritchie, Marylyn D; Borthwick, Kenneth M; Kiryluk, Krzysztof; Mentch, Frank D; Sleiman, Patrick M; Karlson, Elizabeth W; Verma, Shefali S; Zhu, Yineng; Vasan, Ramachandran S; Yang, Qiong; Denny, Josh C; Roden, Dan M; Gerszten, Robert E; Wang, Thomas J.
Afiliación
  • Mosley JD; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN.
  • Benson MD; Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (M.D.B.).
  • Smith JG; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (M.D.B., M.S.H., R.E.G.).
  • Melander O; Molecular Epidemiology and Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden (J.G.S., O.M.).
  • Ngo D; Molecular Epidemiology and Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Malmö, Sweden (J.G.S., O.M.).
  • Shaffer CM; Department of Medicine and the Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston (D.N.).
  • Ferguson JF; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN.
  • Herzig MS; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN.
  • McCarty CA; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (M.D.B., M.S.H., R.E.G.).
  • Chute CG; University of Minnesota Medical School, Duluth Campus (C.A.M.).
  • Jarvik GP; Schools of Medicine, Public Health, and Nursing, Johns Hopkins University, Baltimore, MD (C.G.C.).
  • Gordon AS; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle.
  • Palmer MR; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle.
  • Crosslin DR; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle.
  • Larson EB; Biomedical Informatics and Medical Education (D.R.C.), University of Washington, Seattle.
  • Carrell DS; Departments of Medicine (J.P.J., A.S.G., M.R.P., E.B.L.), University of Washington, Seattle.
  • Kullo IJ; Kaiser Permanente Washington Health Research Institute, Seattle, WA (E.B.L., D.S.C.).
  • Pacheco JA; Kaiser Permanente Washington Health Research Institute, Seattle, WA (E.B.L., D.S.C.).
  • Peissig PL; Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (I.J.K.).
  • Brilliant MH; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.A.P.).
  • Kitchner TE; Biomedical Informatics Research Center (P.L.P., J.G.L.), Marshfield Clinic Research Institute, WI.
  • Linneman JG; Center for Computational and Biomedical Informatics (M.H.B., T.E.K.), Marshfield Clinic Research Institute, WI.
  • Namjou B; Center for Computational and Biomedical Informatics (M.H.B., T.E.K.), Marshfield Clinic Research Institute, WI.
  • Williams MS; Biomedical Informatics Research Center (P.L.P., J.G.L.), Marshfield Clinic Research Institute, WI.
  • Ritchie MD; Cincinnati Children's Hospital Medical Center and University of Cincinnati, OH (B.N.).
  • Borthwick KM; Genomic Medicine Institute (M.S.W.), Geisinger Health System, Danville, PA.
  • Kiryluk K; Departments of Bioinformatics and Genetics (M.D.R.), University of Pennsylvania, Philadelphia.
  • Mentch FD; Biomedical and Translational Informatics (K.M.B.), Geisinger Health System, Danville, PA.
  • Sleiman PM; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY (K.K.).
  • Karlson EW; Center for Applied Genomics, Children's Hospital of Philadelphia, PA (F.D.M., P.M.S.).
  • Verma SS; Center for Applied Genomics, Children's Hospital of Philadelphia, PA (F.D.M., P.M.S.).
  • Zhu Y; Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (E.W.K.).
  • Vasan RS; Perelman School of Medicine, Department of Genetics (S.S.V.), University of Pennsylvania, Philadelphia.
  • Yang Q; Department of Biostatistics, Boston University School of Public Health, MA (Y.Z., Q.Y.).
  • Denny JC; Department of Medicine, Boston University School of Medicine, MA (R.S.V.).
  • Roden DM; Department of Biostatistics, Boston University School of Public Health, MA (Y.Z., Q.Y.).
  • Gerszten RE; Department of Medicine (J.D.M., C.M.S., J.F.F., J.C.D., T.J.W.), Vanderbilt University Medical Center, Nashville, TN.
  • Wang TJ; Biomedical Informatics (J.C.D., D.M.R.), Vanderbilt University Medical Center, Nashville, TN.
Circulation ; 138(22): 2469-2481, 2018 11 27.
Article en En | MEDLINE | ID: mdl-30571344

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedades de las Arterias Carótidas / Proteoma / Estudio de Asociación del Genoma Completo Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Circulation Año: 2018 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedades de las Arterias Carótidas / Proteoma / Estudio de Asociación del Genoma Completo Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Circulation Año: 2018 Tipo del documento: Article