Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation.

Liu, Zhe; Liu, Jian; Dong, Xichen; Hu, Xin; Jiang, Yuliang; Li, Lina; Du, Tan; Yang, Lei; Wen, Tao; An, Guangyu; Feng, Guosheng

Liu, Zhe; Liu, Jian; Dong, Xichen; Hu, Xin; Jiang, Yuliang; Li, Lina; Du, Tan; Yang, Lei; Wen, Tao; An, Guangyu; Feng, Guosheng.

Afiliación

Liu Z; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Liu J; Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Dong X; Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Hu X; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Jiang Y; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Li L; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Du T; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Yang L; Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Wen T; Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
An G; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Feng G; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

J Cell Mol Med ; 23(3): 2083-2092, 2019 03.

Article en En | MEDLINE | ID: mdl-30637914

Asunto(s)

Antígenos de Carbohidratos Asociados a Tumores/genética; Neoplasias Colorrectales/genética; Neoplasias Colorrectales/patología; Transición Epitelial-Mesenquimal/genética; Genes ras/genética; Metástasis de la Neoplasia/genética; Metástasis de la Neoplasia/patología; Línea Celular Tumoral; Movimiento Celular/genética; Regulación hacia Abajo/genética; Regulación Neoplásica de la Expresión Génica/genética; Células HCT116; Células HEK293; Humanos; Chaperonas Moleculares/genética; Regulación hacia Arriba/genética

Palabras clave

Cosmc; EMT; H-Ras; Tn antigen; colorectal cancer; metastasis

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Antígenos de Carbohidratos Asociados a Tumores / Neoplasias Colorrectales / Genes ras / Transición Epitelial-Mesenquimal / Metástasis de la Neoplasia Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article

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