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Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing.
Huo, Zijun; Tu, Jian; Xu, An; Li, Yan; Wang, Donghui; Liu, Mo; Zhou, Ruoji; Zhu, Dandan; Lin, Yu; Gingold, Julian A; Yen, Chia-Jui; Xiao, Haipeng; Zhao, Ruiying.
Afiliación
  • Huo Z; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR China.
  • Tu J; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Department of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR China.
  • Xu A; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Li Y; Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR China.
  • Wang D; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, PR China.
  • Liu M; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Zhou R; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; The University of Texas, MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.
  • Zhu D; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Lin Y; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Guangdong Research Center of Metabolic Diseases of Integrated Western and Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 51
  • Gingold JA; Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
  • Yen CJ; Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
  • Xiao H; Department of Endocrinology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR China. Electronic address: xiaohp@mail.sysu.edu.cn.
  • Zhao R; Department of Integrative Biology and Pharmacology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Electronic address: ruiying.zhao@uth.tmc.edu.
Stem Cell Res ; 34: 101360, 2019 01.
Article en En | MEDLINE | ID: mdl-30640060

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Técnicas de Cultivo de Célula / Células Madre Embrionarias Humanas / Nucleasas de los Efectores Tipo Activadores de la Transcripción / Edición Génica / Mutación Idioma: En Revista: Stem Cell Res Año: 2019 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Técnicas de Cultivo de Célula / Células Madre Embrionarias Humanas / Nucleasas de los Efectores Tipo Activadores de la Transcripción / Edición Génica / Mutación Idioma: En Revista: Stem Cell Res Año: 2019 Tipo del documento: Article