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Does In Vitro Cytochrome P450 Downregulation Translate to In Vivo Drug-Drug Interactions? Preclinical and Clinical Studies With 13-cis-Retinoic Acid.
Stevison, Faith; Kosaka, Mika; Kenny, Jane R; Wong, Susan; Hogarth, Cathryn; Amory, John K; Isoherranen, Nina.
Afiliación
  • Stevison F; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA.
  • Kosaka M; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Kenny JR; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Wong S; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Hogarth C; The Center for Reproductive Biology, School of Molecular Biosciences, Washington State University, Pullman, Washington, USA.
  • Amory JK; Department of Medicine, University of Washington, Seattle, Washington, USA.
  • Isoherranen N; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA.
Clin Transl Sci ; 12(4): 350-360, 2019 07.
Article en En | MEDLINE | ID: mdl-30681285
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Isotretinoína / Regulación hacia Abajo / Sistema Enzimático del Citocromo P-450 / Interacciones Farmacológicas Tipo de estudio: Prognostic_studies Idioma: En Revista: Clin Transl Sci Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Isotretinoína / Regulación hacia Abajo / Sistema Enzimático del Citocromo P-450 / Interacciones Farmacológicas Tipo de estudio: Prognostic_studies Idioma: En Revista: Clin Transl Sci Año: 2019 Tipo del documento: Article