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Modeling the Chronification Tendency of Liver Infections as Evolutionary Advantage.
Reisch, Cordula; Langemann, Dirk.
Afiliación
  • Reisch C; Institute of Computational Mathematics, AG PDE, TU Braunschweig, Universitätsplatz 2, 38106, Braunschweig, Germany. c.reisch@tu-bs.de.
  • Langemann D; Institute of Computational Mathematics, AG PDE, TU Braunschweig, Universitätsplatz 2, 38106, Braunschweig, Germany.
Bull Math Biol ; 81(11): 4743-4760, 2019 11.
Article en En | MEDLINE | ID: mdl-30891676
Here, we discuss how the tendency of a liver infection to chronify can be seen as an evolutionary advantage for infected individuals. For this purpose, we present a set of reaction-diffusion equations as a mathematical model of viral liver infections, which allows chronic and acute courses of the liver infection. We introduce a cumulative wealth function, and finally, we show that an immune response favoring the chronification is evolutionary advantageous at the same time.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Evolución Biológica / Hepatitis Crónica / Hepatitis Viral Humana / Modelos Biológicos Idioma: En Revista: Bull Math Biol Año: 2019 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Evolución Biológica / Hepatitis Crónica / Hepatitis Viral Humana / Modelos Biológicos Idioma: En Revista: Bull Math Biol Año: 2019 Tipo del documento: Article