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Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology.
Wang, Yiran; Xu, Chongchong; Ma, Lin; Mou, Yongchao; Zhang, Bowen; Zhou, Shanshan; Tian, Yue; Trinh, Jessica; Zhang, Xiaoqing; Li, Xue-Jun.
Afiliación
  • Wang Y; Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
  • Xu C; Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, USA.
  • Ma L; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.
  • Mou Y; Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
  • Zhang B; Key Laboratory of Reconstruction and Regeneration of Spine and Spinal Cord Injury, Ministry of Education, Shanghai, China.
  • Zhou S; Key Laboratory of Neuroregeneration of Shanghai Universities, Tongji University, School of Medicine, Shanghai, China.
  • Tian Y; Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, USA.
  • Trinh J; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.
  • Zhang X; Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
  • Li XJ; Brain and Spinal Cord Innovative Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Life Sci Alliance ; 2(2)2019 04.
Article en En | MEDLINE | ID: mdl-30910806
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Atrofia Muscular Espinal / Genes Reporteros / Evaluación Preclínica de Medicamentos / Estabilidad Proteica Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Life Sci Alliance Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Atrofia Muscular Espinal / Genes Reporteros / Evaluación Preclínica de Medicamentos / Estabilidad Proteica Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Life Sci Alliance Año: 2019 Tipo del documento: Article