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Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration.
Durante, Valentina; de Iure, Antonio; Loffredo, Vittorio; Vaikath, Nishant; De Risi, Maria; Paciotti, Silvia; Quiroga-Varela, Ana; Chiasserini, Davide; Mellone, Manuela; Mazzocchetti, Petra; Calabrese, Valeria; Campanelli, Federica; Mechelli, Alessandro; Di Filippo, Massimiliano; Ghiglieri, Veronica; Picconi, Barbara; El-Agnaf, Omar M; De Leonibus, Elvira; Gardoni, Fabrizio; Tozzi, Alessandro; Calabresi, Paolo.
Afiliación
  • Durante V; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • de Iure A; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Loffredo V; Laboratory of Experimental Neurophysiology, IRCCS San Raffaele Pisana, Rome, Italy.
  • Vaikath N; Institute of Cellular Biology and Neurobiology, National Research Council, Monterotondo (Rome), Italy.
  • De Risi M; PhD Program in Behavioral Neuroscience, Sapienza University of Rome, Italy.
  • Paciotti S; Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, Qatar.
  • Quiroga-Varela A; Telethon Institute of Genetics and Medicine, Telethon Foundation, Pozzuoli (NA), Italy.
  • Chiasserini D; Department of Experimental Medicine, Section of Physiology and Biochemistry, University of Perugia, Perugia, Italy.
  • Mellone M; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Mazzocchetti P; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Calabrese V; Department of Pharmacological and Biomolecular Sciences, University of Milan, Italy.
  • Campanelli F; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Mechelli A; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Di Filippo M; Laboratory of Experimental Neurophysiology, IRCCS San Raffaele Pisana, Rome, Italy.
  • Ghiglieri V; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Picconi B; Laboratory of Neurophysiology, Santa Lucia Foundation, IRCCS, Rome, Italy.
  • El-Agnaf OM; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • De Leonibus E; Neurological Clinic, Department of Medicine, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy.
  • Gardoni F; Laboratory of Neurophysiology, Santa Lucia Foundation, IRCCS, Rome, Italy.
  • Tozzi A; Department of Philosophy, Human, Social and Educational Sciences, University of Perugia, Perugia, Italy.
  • Calabresi P; Laboratory of Experimental Neurophysiology, IRCCS San Raffaele Pisana, Rome, Italy.
Brain ; 142(5): 1365-1385, 2019 05 01.
Article en En | MEDLINE | ID: mdl-30927362
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sinapsis / Percepción Visual / Receptores de N-Metil-D-Aspartato / Cuerpo Estriado / Alfa-Sinucleína / Memoria Espacial Idioma: En Revista: Brain Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Sinapsis / Percepción Visual / Receptores de N-Metil-D-Aspartato / Cuerpo Estriado / Alfa-Sinucleína / Memoria Espacial Idioma: En Revista: Brain Año: 2019 Tipo del documento: Article