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Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.
Kaieda, Akira; Takahashi, Masashi; Fukuda, Hiromi; Okamoto, Rei; Morimoto, Shinji; Gotoh, Masayuki; Miyazaki, Takahiro; Hori, Yuri; Unno, Satoko; Kawamoto, Tomohiro; Tanaka, Toshimasa; Itono, Sachiko; Takagi, Terufumi; Sugimoto, Hiroshi; Okada, Kengo; Snell, Gyorgy; Bertsch, Ryan; Nguyen, Jasmine; Sang, Bi-Ching; Miwatashi, Seiji.
Afiliación
  • Kaieda A; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Takahashi M; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Fukuda H; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Okamoto R; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Morimoto S; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Gotoh M; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Miyazaki T; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Hori Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Unno S; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Kawamoto T; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Tanaka T; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Itono S; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Takagi T; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Sugimoto H; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Okada K; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Snell G; Takeda California, 10410 Science Center Drive, San Diego, CA, 92121, USA.
  • Bertsch R; Takeda California, 10410 Science Center Drive, San Diego, CA, 92121, USA.
  • Nguyen J; Takeda California, 10410 Science Center Drive, San Diego, CA, 92121, USA.
  • Sang BC; Takeda California, 10410 Science Center Drive, San Diego, CA, 92121, USA.
  • Miwatashi S; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.
ChemMedChem ; 14(10): 1022-1030, 2019 05 17.
Article en En | MEDLINE | ID: mdl-30945818
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piridinas / Piridonas / Proteínas Quinasas p38 Activadas por Mitógenos / Inhibidores de Proteínas Quinasas / Imidazoles / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Piridinas / Piridonas / Proteínas Quinasas p38 Activadas por Mitógenos / Inhibidores de Proteínas Quinasas / Imidazoles / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: ChemMedChem Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2019 Tipo del documento: Article